Dr. Sean Cleary is a clinician-scientist at Mount Sinai Hospital and the University Health Network. His research interests are focused on the genetic epidemiology of liver, pancreas and colorectal cancer, and his clinical practice is in the surgical management of these malignancies. During his residency, Dr. Cleary obtained a Master’s of Science in Cancer Genetics under the supervision of Dr. Steven Gallinger, and completed a MHSc in Public Health and Epidemiology in the Department of Public Health Sciences.
He completed a fellowship in Pancreatic and Hepatobiliary Surgical Oncology and Transplantation at the Toronto General Hospital after finishing his General Surgery Residency training at the University of Toronto.
Dr. Cleary is focused on exploring how the risk of developing cancer is influenced by our genetic makeup as well as the environment around us. Individual genetic variants, either alone or in combination with other variants, can contribute small incremental changes to our cancer risk. Genetic factors can also influence our susceptibility to environmental factors that either increase, or decrease, our risk of cancer. Dr. Cleary is working to understand the relationship between genetic variation and environmental exposures, to help identify high-risk groups in our population and provide insight into the etiologic mechanisms of cancer.
His clinical interests include the surgical treatment of pancreatic, hepatic and biliary malignancies as well as minimally invasive hepatobiliary surgery
His research interests are focused on the genetic epidemiology of liver, pancreas and colorectal cancer, and his clinical practice is in the surgical management of these malignancies.